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Re: provigil+-alpha/beta blocker? }} mike99

Posted by sdb on March 5, 2006, at 18:28:55

In reply to Re: provigil+-alpha/beta blocker? }} mike99 sdb, posted by mike99 on March 5, 2006, at 17:37:22

>>although none are completely selective

Yes. The most selective betablocker for beta1-receptors is nebivolol. But nebivolol has weak affinity. It's more likely that nebivolol acts antihypertensive through NO release.

Most betablockers elevate LDL but laboratory research has shown that there is no increase in (intima/media) thickness of blood vessels. This is postulated due to antioxidative properties, stabilizing heart rate, more smooth pulsus improving haemodynamics.





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