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Re: Coreg (carvedilol) ed_uk

Posted by mike99 on March 4, 2006, at 15:54:11

In reply to Re: Coreg (carvedilol), posted by ed_uk on March 3, 2006, at 17:14:52

> Hi Mike
>
> I assume you're considering taking carvedilol to reduce the cardiovascular toxicity which you've previously experienced on amphetamines and methylphenidate.

Exactly...I'm actually considering a trial of Provigil, and despite it's reduced cardiovascular activation I'm pretty confident I'd also need an alpha/beta blocker on board.

> I'm not sure carvedilol would be the best option. You might want to consider taking a beta blocker (eg atenolol or bisoprolol) in combination with an alpha blocker (eg doxazosin) instead. This way, you could adjust the dosage of the beta blocker according to your heart rate and the alpha blocker according to your BP etc. This is an oversimplification but I'm sure you understand what I'm getting at. With carvedilol, you wouldn't have as much 'flexibility'.

...I get your point right on--that's a great idea. Thanks for the suggestion. In addition to the 'flexibility' you mention, it would also allow me to use a cardioselective beta blocker like atenolol as you suggest. One thing I really don't like about carvedilol is it's non-selectivity of beta blockade.

I'll run this by my doc and post if it works out. Thanks again for your response and input.

Mike


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poster:mike99 thread:614419
URL: http://www.dr-bob.org/babble/20060304/msgs/615915.html