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Lithium: to barbara and carebear

Posted by ed_uk on March 22, 2005, at 13:25:17

In reply to Re: Dysphoric Mania ed_uk, posted by barbaracat on March 22, 2005, at 12:23:38


>New research is showing that the therapeutic level of lithium may be too high and have lowered the bottom end to .4 instead .6.

That's interesting, I think it's 'always' been 0.4 in the UK. I just looked in a book from 12 years ago, it was 0.4 then!

> He felt good at 900mg but his doctor is insisting on increasing until he reaches the 'therapeutic window'.

IMHO, every patient has their own individual therapeutic window.

>My levels aren't even in the ballpark, but I dug in my heels with my pdoc and luckily, he reluctantly agreed that a non-therpeutic dose seemed to be working.

What's your level? Maybe 0.3? Just a random guess!

>I'd have to agree with you that Li doses do not need to be so high.

My friend's pdoc wanted him at a minimum of 0.8 for unipolar depression w/ prominent fatigue! This was despite the fact that his depression got worse at 1200mg (0.7), she wanted to increase to 1500mg- he refused! I don't think he'd even be able to get out of bed if he was on 1500mg.





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