Posted by Sad Panda on October 14, 2004, at 7:31:59
In reply to Re: Selegiline Sexual Side Effects, posted by Iansf on October 14, 2004, at 0:07:27
> I've never heard of using a TCA to counteract anorgasmia. In fact, it was my impression tricyclics commonly cause sexual dysfunction. What one are you using, and at what dose? Does it truly work? If it does, why isn't this common knowledge among psychiatrists?
>
>I take 100mg of Amitriptyline as well as 75mg of Effexor, before this I took 125mg of Nortriptyline with 150mg of Effexor & before that I took 225mg of Effexor with 30mg of Remeron.
TCA’s taken at full antidepressant doseages can cause erectile dysfunction, but taken at lower dosages this is fairly unlikely to happen. Most TCA with the exception of Imipramine & Desipramine are good 5-HT2A antagonists. SSRI's, Effexor & probably Cymbalta cause anorgasmia by raising serotonin levels which cause adverse reactions at some serotonin receptors especially 5-HT2A. The ones that are good to combine with SSRI’s & Effexor from least sedating to most sedating are Nortriptyline, Amitriptyline, Trimipramine & Doxepin. Other AD’s that are useful are Remeron & Trazodone. Most AP’s are also 5-HT2A antagonists, Risperdal & Zyprexa at very low doseages are good, but I would put them last on the list. Other SSRI induced problems that these fix are insomnia, heat problems & anxiety. If you are taking an SSRI such as Zoloft or Lexapro or you are taking Effexor then I would recommend a trial of Nortriptyline as you might find that it has very minimal side effects as I did.
Cheers,
Paul.
poster:Sad Panda
thread:402677
URL: http://www.dr-bob.org/babble/20041012/msgs/402908.html