Posted by utopizen on October 13, 2004, at 13:42:57
In reply to Selegiline Sexual Side Effects, posted by sfy on October 13, 2004, at 13:03:27
> Has anyone else had this experience with selegiline? Does this effect point to some other approach I should try for my anhedonia/dysthymia? (Parnate is probably my next step.)
>I'm about to get 10mg/day of Selegiline myself, but don't kid yourself- the reason why it's being developed in patch form is to deliver 20-25mg/day without needing a dietary restriction. 10mg/day of Seligiline alone is not going to do a thing for your depression, I hate to burst your bubble.
I'm planning to take it along with 1500mg of DLPA, a supplement found in high-protein foods, 20mg of Celexa, and maybe some 60mg-120mg Cymbalta down the road-- along with my 60mg of Adderall/day and 3mg of Klonopin/day. And during Christmas break, I think I'll finally experiment with Strattera to see if it helps me lower my Adderall dose.
If you haven't tried Cymbalta between 60-120mg for a few months, Parnate is probably not too wise, IMHO. Cymbalta is a powerful and potent new drug that helps to elevate mood, reduce anxiety, and increase motivation/drive/energy, according to reports here and partially according to insidecymbalta.com.
Cymbalta, according to Eli Lilly, found signfigigant results within 1-2 weeks of patients taking 60mg/day, and maximum results achieved by the 4th week (you may require up to 120mg/day, and it may take a couple of months before calling it quits).
You can also always try adding about 300mg of Lithium to Cymbalta if it doesn't work fully for you, as many depressives find success with that. Lamictal also is proven to help boost the efficacy of antidepressants in patients who don't find relief from them. Antipsychotics like Risperdal, while incredibly painstaking to take for the first few weeks, often produces substantial gains when it's added to an antidepressant as well.
Parnate, though, gosh- I would have to think, if you tried really high doses of all these things in a sort of combination, and tried them for like 3 months, and you still didn't find relief, MAYBE it's an option. But it's an unlikely one. I doubt many doctors would give it to you before trying to up a dose of an antipsychotic, and if that didn't work, consider ECT.
poster:utopizen
thread:402677
URL: http://www.dr-bob.org/babble/20041012/msgs/402697.html