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Re: Selegiline Sexual Side Effects

Posted by gromit on October 15, 2004, at 23:36:18

In reply to Re: Selegiline Sexual Side Effects » Iansf, posted by Sad Panda on October 14, 2004, at 7:31:59


> I take 100mg of Amitriptyline as well as 75mg of Effexor, before this I took 125mg of Nortriptyline with 150mg of Effexor & before that I took 225mg of Effexor with 30mg of Remeron.
>
> TCA’s taken at full antidepressant doseages can cause erectile dysfunction, but taken at lower dosages this is fairly unlikely to happen. Most TCA with the exception of Imipramine & Desipramine are good 5-HT2A antagonists. SSRI's, Effexor & probably Cymbalta cause anorgasmia by raising serotonin levels which cause adverse reactions at some serotonin receptors especially 5-HT2A. The ones that are good to combine with SSRI’s & Effexor from least sedating to most sedating are Nortriptyline, Amitriptyline, Trimipramine & Doxepin. Other AD’s that are useful are Remeron & Trazodone. Most AP’s are also 5-HT2A antagonists, Risperdal & Zyprexa at very low doseages are good, but I would put them last on the list. Other SSRI induced problems that these fix are insomnia, heat problems & anxiety. If you are taking an SSRI such as Zoloft or Lexapro or you are taking Effexor then I would recommend a trial of Nortriptyline as you might find that it has very minimal side effects as I did.

Geez, I take 25mg of Elavil and I'm way tired the next day, and this hasn't gone away over time. Do you find Nortriptyline less sedating than Amitriptyline? I would really like to find something to help with the anorgasmia that doesn't knock me out the next day, I can barely stay awake as it is. My meds currently are

Lexapro 20mg
Lamictal 200mg
Buspar 30mg
Provigil 300mg
Amitrypyline 25mg

Thanks
Rick


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