Psycho-Babble Medication | about biological treatments | Framed
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Posted by linkadge on August 17, 2004, at 8:27:32

In reply to Re: TRICYCLICS: Is there a best one?, posted by SLS on August 17, 2004, at 6:08:43

"It's things like this that have me question the necessity for neurogenesis to occur before experiencing an improvement of depression."

I have come to beleieve that recovering from depression is biphasic. Think of it this way. You have a badly broken leg that causes you severe pain. Your doctor says that the pain will lesson as the bone regenerates and heals itself. That evening you pop a vicodin and notice that the pain is completely gone. You say to yourself, "screw bone healing, all I need is vicodin!" That evening the pill wears off and you realize that you really didn't fully recover.

What I am trying to saying is this. Antidepressants can act as both emotional analgesics and promoters of neurogenesis. The angalgesic part can be useful but misleading. For instance heroin brings prompt releif of depression without neurogenesis, but if you notice that at the end of the day you don't feel like you've got anywhere on cocaine. Antidepressants that promote neurogenesis are much more helpfull in the long run. They can heal the bone underneath so that breakage is less likely. Take lithium for example, this is like the oppsoite of cocaine in that it has zilch emotinal analgesic potenetial but it does promote neurogenesis. It is the neurogenesis that finds plausable ways to deal with the problems that contributed to the depression in the first place.

I think it is a double sided coin but that the neurogenesis certainly plays a part in restructuring the brain to make it more resilitan to emotional turmoil.

Just my thoughts.





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