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Re: TRICYCLICS: Is there a best one?

Posted by SLS on August 16, 2004, at 8:45:02

In reply to Re: TRICYCLICS: Is there a best one?, posted by King Vultan on August 16, 2004, at 7:54:28

> I guess my thought would be that if the imipramine is working for you, there's perhaps not a great deal of incentive to change. If a person is looking for something similar with less anticholinergic effects, nortriptyline would probably be a good alternative.
>
> Todd

I really prefer the way I feel on nortriptyline to desipramine. It feels like a more "whole" antidepressant effect. Unfortunately, there is no stable window of efficacy for me. I just can't use the drug. I wish I could.

I can't stress enough how important it is to aim for the bullseye with nortriptyline dosage. Too high a dosage is as bad as too low a dosage. Use blood tests as guide, but assess clinical effect through experimentation within the therapeutic range.

- Scott

 

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