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Re: Sublingual Selegiline - more questions

Posted by fab on October 15, 2003, at 23:17:44

In reply to Re: Sublingual Selegiline - more questions hok, posted by not exactly on March 19, 2003, at 3:04:46

I've taken very low dosages of selegiline with no hint of it causing depression... anyway, who manufactures the new sublingual? I'm interested!!
Thanks!

RE: > > A word of warning though, low doses of selegiline without an AD may induce depression.
>
> Yes, I've noticed that. As I mentioned before, "Less than 15 [mg/day of oral selegiline] was unreliable and made me feel almost bipolar - unpredictable and severe mood swings."
>
> I found that low-dose selegiline worked well only when I combined it with something else. The three augmentation agents that worked best were phenylalanine, chocolate, and Ritalin. Any of these 3 would turn low-dose selegiline into a consistently effective antidepressant. But none worked so well that they ended my quest for a better solution.
>
> > Hopefully, the buspar will help buffer this effect.
>
> Since Buspar is working well for me as an AD, I was thinking that it too might serve to stabilize the positive effects of selegiline. And hopefully the selegiline will give me a bit more energy and further reduce the anhedonia. There's really only one way to find out for sure. But first, I want to see what the Buspar/Klonopin combo will do with dose optimizing and patiently waiting for the full plateau.
>
> > By the way, did you ever have any problems with selegiline and verbal fluency? It seems deprenyl is great for word recall, but I seem to get "caught up" a lot in my conversations. There is some reference in the reserch to a decrease in verbal fluency on selegiline and I was wondering if you ever noticed this while on the patch (or did the MAO-A inhibition help to balance this out).
>
> I've noticed that my verbal fluency and word recall vary significantly with different meds, but I don't remember selegiline (oral or transdermal) having a negative effect on either capability.
>
> - Bob
>


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