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Re: Adrafinil? Sulpiride? » SLS

Posted by KarenB on July 4, 2000, at 12:40:20

In reply to Re: Adrafinil? Sulpiride? » KarenB, posted by SLS on July 4, 2000, at 9:28:43

> Dear Karen,
>
> Thank you SO, SO much!

No problem!

> Your comments regarding low-dose sulpiride and mood stabilization are fascinating and extremely important.
>
> In what ways has sulpiride acted as a mood stabilizer? How was your mood unstable previously?

No more raging irritability, irrational anger about petty things, I was just more steady and able to cope, even in high stress situations.

> "Anergic" means without energy. Bipolar depression is usually very anergic (low-energy), and in many ways appears similar to atypical unipolar depression.

> What is it about your case that has led to a diagnosis of bipolar disorder?

The irritability and irrational anger sound a lot like mania, don't they? That's what two different docs thought. It was my research that revealed the ADD. I probably have both, although I don't really want to face that possibility right now. My doctor wants me to see Dr. Steven Dobovsky, a specialist in both disorders but he is very expensive, doesn't take my insurance and is booked until Winter.

> ADD / ADHD and bipolar disorder often occur simultaneously. I believe that Provigil is currently being studied for use in ADD. Initial results are encouraging. However, I could not find anything on Medline regarding this. I imagine adrafinil would have the same utility. I can find nothing in the Provigil (modafinil) package insert that would suggest that it cannot be combined with Dexedrine, Adderal, or Ritalin. The only interaction listed is that Ritalin may delay the absorption of Provigil by one hour if they are taken simultaneously. I do not know to what extent this information is applicable to adrafinil. I'm sure your doctor will be able to tell you with certainty. I included relevant information below. Perhaps adrafinil will improve your mood without improving ADD. In this case, adding a stimulant may be desirable.

Using another stimulant plus Adrafinil seems like it would be redundant. I am on the Adrafinil alone right now.

> Did sulpiride produce any improvement in PMS?

YES! Without menses, there is no PMS and none of the awful physical and psychological symptoms. This is probably one reason it was so stabilizing for me. I'd be interested to see what the effect is in a male.

> I can't tell you how much it means to me that you posted such a detailed reply. Thanks again.

:)
>
> Sincerely and Appreciatively,
> Scott
>
>
> P.S. I haven't menstruated since beginning sulpiride either. I don't know how to feel about that.

Ha ha...

Have a good 4th!

Karen


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