Posted by SLS on July 3, 2000, at 21:02:07
In reply to Re: Adrafinil? » Lynne, posted by KarenB on July 3, 2000, at 16:06:29
> BTW, Amisulpride may be a good choice to augment this drug - it has been for JohnL and I have firsthand experience with Sulpiride augmentation of a psychostimulant, which gave me the best relief I have ever had from my depression symptoms (apathy, fatigue, excessive daytime sleepiness, irritability, irrational and suicidal ideology, some social anxiety plus ADD). Sulpiride is very close to amisulpride, chemically and has some antidepressant action, as well. While the psychostimulant provided energy, the Sulpiride relieved my physical symptoms of fatigue, heaviness and social anxiety. I was as well as I have ever been while on these meds. I have been attempting for the past several months to find a combo, stateside, to give similar results but have always come up short. I am almost ready to order overseas and be my sane self once again. I don't know how much longer I can take the depression and mood swings when I know of something that actually works.
Dear Karen,I have been taking sulpiride 50mg a day, first thing in the morning, for about 12 days. I thought I felt a little something in the morning after taking it for the first few days. It is not helping right now, but neither is it producing any sedation. I take this to be a good sign. I can't help but to be hopeful. I could use a little help before seeing my doctor on Wednesday. I hope it's not too much trouble for you to answer a few questions. More than a few questions. Sorry.
When you had such great success with sulpiride:1. What dosage of sulpiride were you taking, and how did you divide your doses during the day?
2. What brand-name did you use, and what was the dosage of each pill?
3. Where did you get it?
4. How much did it cost?
5. What other drugs were you taking at the time? Stimulant?
6. How long did it take to work?
7. Were there any side effects?
8. Why did you stop taking sulpiride?
9. Why are you no longer taking a stimulant?
If sulpiride is partially effective, I will need to choose other drugs to add to it. I was thinking about using Provigil, but both you and JohnL describe adrafinil as being better. The other route involves going back to an MAO inhibitor, probably Parnate. Do you have any thoughts? I am also taking Lamictal 300mg. I suffer from an anergic bipolar depression that shares many of the features you describe for your condition.THANKS.
-Scott
poster:SLS
thread:39176
URL: http://www.dr-bob.org/babble/20000630/msgs/39242.html