Posted by michael on June 5, 2000, at 18:54:06
In reply to Re: Amisulpride, Andrew, posted by AndrewB on June 5, 2000, at 18:31:55
This is not entirely, but at least in part, the same question as amisulpride & selegiline thread was addressing. As I think I mentioned, I was wondering about that combo specifically, because both of these meds target the dopamine system.
I was referring to only 10mg selegiline daily, which, at this low dosage, preferentially inhibits MAOI-B. (MAOI-B the one that is supposed to break down dopamine). I've decided to give it a try, however, I am also taking a lower than usual dose of amisulpride - only approx. 12.5mg per day - just a quarter of a 50mg tablet (due to the fact that 50mg/day had me sleeping at least 12 hours/day).
Btw, tried going up to 25mg amisulpride/day, and was tired and lethargic & apathetic... not good. Don't know if that would've been the case w/o the selegiline. I had been taking the selegiline for about 10 - 14 days at the time, and the amisulpride for about 4 - 8 days when I tried the 25mg dose. Sorry, I guess I should've been making notes...
I don't have anything to contribute about other maoi's...
> > Andrew:
> >
> > Thanks for the information and advice. I have never heard of amisulpride being used with a MAOI but admittedly I've never done any research in the area. Has any research been done that demonstrates the safety and effectiveness of doing this? I'm going to check Medline and see what I come up with. I'm curious to see how Seamus does with it. Anyway thanks again.
> >
> Peter,
>
> Can amisulpride be combined with an MAOI? That is an important question. I think I can get an answer but give me some time. Keep checking back.
>
> AndrewB
poster:michael
thread:34436
URL: http://www.dr-bob.org/babble/20000603/msgs/36183.html