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Re: Amisulpride, to all

Posted by AndrewB on June 7, 2000, at 20:19:54

In reply to Re: Amisulpride, Andrew and all » SLS, posted by Ant-Rock on June 7, 2000, at 18:44:30

Can an MAOI (Parnate, Nardil) be combined with amisulpride?

I got a response from a psychiatrist who used amisulpride extensively in Columbia. She related that she never used amisulpride in combination with other medications She said that, in her opinion, amisulpride should never be combined with an MAOI. I hope that Anthony and Seamus work closely with their psychiatrists when trying such a combination since this is new territory.

Various dopamine enhancers can induce psychotic symptoms in certain individuals. Though this doesn't seem to be an issue with me, people should be on the look out for this side effect when using dopamine enhancers. Another indication of too much dopamine is decreased mental focus. Dopamine has a bell curve effect on attentiveness, improving it up to a point and thereafter making the mind flighty and less able to focus on things.

As far as research goes concerning the connection between dopamine and depression I can suggest an article entitled 'The role of stress in the pathophysiology of the dopaminergic system' as a good place to start to get an understanding of how dopamine system dysregulation can evolve. To view this article go to www.stockton-press.co.ul/server-java/Propub/stockton/spmp v5 n1 p14 o1.fulltext (note that the spaces on this address should be underline marks> I don't seem to be able to type those marks into this message form.) There are many more articles written on this subject but unfortunately they are not up on the net. You can however search medline abstracts and get an idea of what's out there.

Best wishes,

AndrewB


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