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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 9 of 9. This is the beginning of the thread.
Posted by bkva23 on January 5, 2016, at 0:26:12
As most know gaba is a key neurotransmitter.Its the major inhibitory one used in calming anxiety,mood disorders and seizures.Gaba itself is sold in powder in health stores for outragerous prices but as most know gaba alone doese NOT cross the BLOOD BRAIN BARRIER and needs a carrier.Pharm meds either mimic gaba like Gabapentin or use a synthetic carier like gaba vinvyl which actualy attaches to yess vinyl.
Thee are however some suitable forms of carriers,not many but one is the demonized ghb which used a hydroxy acid as its carrier into the brain.Problem with this is the nutrient is way to powerful and intoxicating however the FDA after banning it from health stores saw fit to make it a pharm made called xyrem you can look that up raising the price at least 10 fold.
The russians were brilliant.They created picamilon which is gaba attached to niacin which is its carrier,so here we have a safe effective carrier any many many people found reliaf from this nutrient which even in russia i believe became also a pharm med.
Well now the GREAT ALMIGHTY FDA plans to actualy band this nutrient.Yes sir,a nutrient unlike ghb that cause no serious mind altering affect,is vey mild in effect,and works.They claim some how its a drug.Google picamilon illegal and see for your selves.My god both ingredients are pure safe nutrients,i cant believe they are attempting this.I truly hope they dont get away with it.
For the record other effective gaba enahcning nutrients are
- L Theanine which raises both gaba and dopamine levels.
- Phenibut another popular russian nutrient that raises gaba but known to be toxic.
- Kava Kava was pretty potent at raising gaba.
- Valerian root is said also to raise gaba
None of these however seemed to have the success of picamlion.
Posted by stan_the_man70 on January 5, 2016, at 3:03:04
In reply to Gaba and the FDA, posted by bkva23 on January 5, 2016, at 0:26:12
How about taurine, ashwagandha, lemon balm? do they help with gaba?
Do glutamine or creatine help with the glutamate cycle?
thanks !
>
> For the record other effective gaba enahcning nutrients are
>
> - L Theanine which raises both gaba and dopamine levels.
>
> - Phenibut another popular russian nutrient that raises gaba but known to be toxic.
>
> - Kava Kava was pretty potent at raising gaba.
>
> - Valerian root is said also to raise gaba
>
> None of these however seemed to have the success of picamlion.
Posted by bkva23 on January 5, 2016, at 3:33:12
In reply to Re: Gaba and the FDA, posted by stan_the_man70 on January 5, 2016, at 3:03:04
I dont know of the others except a lot on taurine.Taurine doesent work on gaba however it is the second most abundant inhibitory nuerotransmitter.Like gaba it calms overfiring nuerons,unlike gaba it even is said to calm electrical current from the brain to body.Taurine does cross the brain more then gaba but its still weak as a nutrient.
Google CAMPREL camprel is taurine attatched to a chemical carrier so it crosses more realy into the brain.Let me look it up hold...Heres a paste
" Background
Acamprosate (a kam' proe sate) is N-acetylhomotaurine, a synthetic amino acid analogue similar to gamma aminobutyric acid (GABA) and taurine that has been shown to decrease alcohol craving in animal models"
There you have it a synthetic version of taurine camprel is being used for alcohol withdrawal.
Lowering glutamate does i believe result in higher levels of gaba but its not something thats gonna be as potent and fast acting as a gaba carier or taurine carrier.
Posted by SLS on January 5, 2016, at 7:32:30
In reply to Re: Gaba and the FDA, posted by stan_the_man70 on January 5, 2016, at 3:03:04
> How about taurine, ashwagandha, lemon balm? do they help with gaba?
>
> Do glutamine or creatine help with the glutamate cycle?
>
> thanks !
>
>
> >
> > For the record other effective gaba enahcning nutrients are
> >
> > - L Theanine which raises both gaba and dopamine levels.
> >
> > - Phenibut another popular russian nutrient that raises gaba but known to be toxic.
> >
> > - Kava Kava was pretty potent at raising gaba.
> >
> > - Valerian root is said also to raise gaba
> >
> > None of these however seemed to have the success of picamlion.
Lamictal (lamotrigine) + NAC (N-acetylcystein) for depression.Maybe anxiety too - not sure. Both drugs inhibit glutamate release and/or production, and are supposed to be complementary and perhaps synergistic. NAC also is transformed in the body to glutathione, a potent antioxidant.
- Scott
Posted by linkadge on January 9, 2016, at 13:10:31
In reply to Gaba and the FDA, posted by bkva23 on January 5, 2016, at 0:26:12
I have used both phenibut and picamillon. I prefer phenibut.
"Phenibut another popular russian nutrient that raises gaba but known to be toxic."
Can you elaborate on the 'toxic' comment? Are you just referring to tolerance and withdrawl?
Linkadge
Posted by rose45 on January 12, 2016, at 6:37:52
In reply to Re: Gaba and the FDA, posted by linkadge on January 9, 2016, at 13:10:31
After reading bkva23 mention picamilon, I decided to order it. I live in the uk and it seems that at the moment it is possible and easy to order. I really want it for sleep as I am on parnate.
I would appreciate any info on whether it is entirely safe to take with parnate, and any idea on dosage and what time of day to take for sleep.
The parnate seems to take care of all anxiety. I am not anxious on it, but I do suffer from lack of energy, and sleepiness during the day, with inability to sleep well at night.
I would appreciate any feedback from anyone who has taken picamilon either on its own or with an maoi. Many thanks.
Posted by former poster on January 14, 2016, at 2:17:30
In reply to Re: Gaba and the FDA, posted by rose45 on January 12, 2016, at 6:37:52
My friend and I tried Picamilon last summer and I found larger doses to be very energising. Quite the opposite effect I was expecting. The smaller doses gave me a odd but calm "feeling". Tried it for about 3 weeks and now I'm afraid to take it again until more data comes out on this stuff.
Posted by rose45 on January 14, 2016, at 4:37:41
In reply to Re: Gaba and the FDA » rose45, posted by former poster on January 14, 2016, at 2:17:30
> My friend and I tried Picamilon last summer and I found larger doses to be very energising. Quite the opposite effect I was expecting. The smaller doses gave me a odd but calm "feeling". Tried it for about 3 weeks and now I'm afraid to take it again until more data comes out on this stuff.
Thanks former poster. Were you also taking other medication at the same time? I tried one tablet yesterday. It was a 100 mg tablet, but since I am on parnate, Im a little worried about it. It seems the effect becomes noticeable after taking it for a while, from what I read.... but I also feel wary of taking it.
Posted by former poster on January 17, 2016, at 1:50:06
In reply to Re: Gaba and the FDA, posted by rose45 on January 14, 2016, at 4:37:41
>Were you also taking other medication at the same time?
I was on a small dose of clonazepam about .5mg a day at the time. Also took an herbal supplement called honokiol with picamilon. Sorry I can't be more help. We really are exploring the unknown mixing meds and supplements.
This is the end of the thread.
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