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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 5 of 5. This is the beginning of the thread.
Posted by linkadge on February 28, 2015, at 9:29:29
Cotinine, a metabolite of nicotine is apparently active as an antidepressant. It has been sold under the brand name "Scotine". I have never heard of this. Is it only available in certain countries?
Linkadge
Posted by rjlockhart37 on February 28, 2015, at 12:27:10
In reply to metabolite of nicotine an antidepressant?, posted by linkadge on February 28, 2015, at 9:29:29
yea i googled it, it's in tobacco, i smoke and i've smoked for a long time and i do notice during times if my mood gets in a slump i usally smoke a ciggerette and feel better for about an hour, i don't know if you ccan get it in a pill form, but yea.....nicotine does help depression my mildly acting as a stimulant to the dopamine and mainly acetylcholine.....
http://en.wikipedia.org/wiki/Nicotinic_acetylcholine_receptordon't encourage to smoke at all but nicotine gum, or a vape could deliever nicotine without the bad stuff from tobacco smoking....
Posted by hello123 on March 1, 2015, at 1:29:52
In reply to Re: metabolite of nicotine an antidepressant?, posted by rjlockhart37 on February 28, 2015, at 12:27:10
the same has been suggested about nicotine itself. tho yeah, theres the problem of addiction.
tho ive been an inpatient a few times, and each time
a strong majority of the other peoole staying as inpatients smoked. so i guess its either the negative effects of smoking make the AD effects of Nicotine or its metabolites less effective. Or in spite of the short term benefits they receive from Nicotine or Cotinine, it ends up not being beneficial, at least for these patients.
Posted by hello123 on March 1, 2015, at 1:47:10
In reply to Re: metabolite of nicotine an antidepressant?, posted by hello123 on March 1, 2015, at 1:29:52
ive just always figured nicotine, and i dont know cotinines mechanism of action but im.guessing its much like nicotines, ends up causimg the brain to adapt to their effects over time, causing ones plasure centers in their brain to be responsive to normally pleasurable activities, and rely on nicotine for pleasure.
Posted by hello123 on March 1, 2015, at 10:40:17
In reply to Re: metabolite of nicotine an antidepressant?, posted by hello123 on March 1, 2015, at 1:47:10
oops, i meant to say ive figured Nicotines effects end up causing the pleasure centers in the brain to be LESS responsive to normally pleasurable activities
This is the end of the thread.
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