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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 14 of 14. This is the beginning of the thread.
Posted by johneangel on September 21, 2010, at 16:09:07
Only the original Nardil works for me and thousands of others. The reformated Nardil of 2003 does not work and has many serious side affects for me and others.
I'm looking for people who have samples of the old Nardil, bright shinny orange pills, that they can send directly to the FDA (Food and Drug Administration) so that the FDA can begin an investigation into the illegal reformulation of Nardil.
"If old samples are available", I will contact the FDA again and ask them to post on dr.-bob.org a message with the FDA address for receiving the samples. If for some reason the FDA cannot do this or this site does not allow such messages, I will obtain the address for the individual at the FDA that will receive the samples and post it on this Forum.
All help in completing this will be appreciated.
very sincerely, johneangel
Posted by Phillipa on September 21, 2010, at 17:13:39
In reply to Have FDA Make Original Nardil available in USA, posted by johneangel on September 21, 2010, at 16:09:07
What a good idea. I know a few will contact them. Phillipa
Posted by former poster on September 22, 2010, at 0:10:59
In reply to Re: Have FDA Make Original Nardil available in USA » johneangel, posted by Phillipa on September 21, 2010, at 17:13:39
Why was Nardil reformulated in 2003? I remember that was the year Nardil pooped out on me. Sorry for asking. I know the answer is somewhere in Psycho-Babble. Could someone direct me to it?
Posted by Tomatheus on September 22, 2010, at 0:27:22
In reply to Re: Have FDA Make Original Nardil available in USA » Phillipa, posted by former poster on September 22, 2010, at 0:10:59
> Why was Nardil reformulated in 2003?
According to documents prepared by the FDA, the goals of the formulation change were to improve the medication's so-called poor disintegration and dissolution properties and to address shelf-life issues.
Tomatheus
Posted by angels78 on September 24, 2010, at 4:21:10
In reply to Re: Have FDA Make Original Nardil available in USA » former poster, posted by Tomatheus on September 22, 2010, at 0:27:22
Nardil still works, google it. Make sure your on the right dose.
Posted by Tomatheus on September 24, 2010, at 17:17:52
In reply to Re: Have FDA Make Original Nardil available in USA » Tomatheus, posted by angels78 on September 24, 2010, at 4:21:10
Angels78,
My understanding is that the current version of Nardil still works for some people, but that a lot of long-time Nardil users experienced a worsening of symptoms and an onset of new side effects when the formulation was changed in 2003.
For me, Nardil stopped working after I received what was probably a bad batch of the medication. I noticed a very sudden worsening of my depressive symptoms after I started taking the pills from my suspected bad batch, and I also became *extremely* agitated. When Nardil worked for me, I actually felt less agitated on it, so my suspicion is that there was something very wrong with the last batch of Nardil that I received. Others have also reported receiving bad batches, although I haven't heard any recent reports of bad batches.
If you read messages on this board for long enough, you'll find that Nardil doesn't work for everybody. Just read former poster's post in this thread. The medication stopped working for him/her in 2003 just as it did for a lot of others. How the current version of Nardil differs from the old version is hard to quantify, considering that no published studies have ever compared the efficacy of old Nardil with new Nardil. However, it is my belief that it was no coincidence that so many people started having problems with the medication around the same time.
How long have you been at your current dose of Nardil?
Tomatheus
Posted by former poster on September 24, 2010, at 17:47:54
In reply to Re: Have FDA Make Original Nardil available in USA » angels78, posted by Tomatheus on September 24, 2010, at 17:17:52
I was on Nardil approx. 10 years. When I got the new pills around 2003 I had the same feeling, like it was a bad batch. I think that was around the time my Dr. convinced me to take Dextroamphetamine with Nardil which made me feel "cured" of any depression or anxiety.
Posted by angels78 on September 25, 2010, at 22:32:26
In reply to Re: Have FDA Make Original Nardil available in USA » angels78, posted by Tomatheus on September 24, 2010, at 17:17:52
There lies your answer. I never took Nardil prior to 2003 and I don't suffer from depression, just social phobia/agorphobia/panic attacks. I'm at 75mg a day, and it has helped me big time. This is my second time taking it after realizing the first time all the mistakes I made including eating like a fat pig, this time I excerise and eat healthy and haven't gained a pound. But Nardil has helped me so much in social settings, and I know it can help me a bit more at 90 mg.
Posted by Tomatheus on September 26, 2010, at 0:15:43
In reply to Re: Have FDA Make Original Nardil available in USA » Tomatheus, posted by angels78 on September 25, 2010, at 22:32:26
Angels78,
I don't doubt that Nardil has helped you tremendously. When it works, Nardil can make a world of a difference for people suffering with a range of psychiatric conditions. So, I'm very happy for you that Nardil has helped you in social situations, and I hope that it continues to do so.
I guess the main point that I was trying to make in my last post was that Nardil doesn't work for everybody. It is also not unheard of for Nardil users to to respond very favorably (perhaps too favorably in some cases) to the medication for two weeks or maybe more before losing their response. That was what happened when I took film-coated Nardil -- I responded for about two weeks before my symptoms returned. Of course, not everybody responds to Nardil in the same way. You may be one of those people who finds the "new" Nardil to be highly effective over a long period of time.
Before I finish, I'd like to congratulate you on maintaining your weight while taking Nardil. I know from experience that avoiding weight gain on Nardil can be extremely difficult, and I commend you for doing the necessary work to maintain your weight.
Tomatheus
Posted by angels78 on September 26, 2010, at 2:37:24
In reply to Re: Have FDA Make Original Nardil available in USA » angels78, posted by Tomatheus on September 26, 2010, at 0:15:43
Thanks. If Nardil only worked for you the first two weeks, perhaps you were only feeling the Europhia and I'm curious what dose were you at, and what is your weight at the time you were taking Nardil?
Posted by Tomatheus on September 26, 2010, at 12:08:41
In reply to Re: Have FDA Make Original Nardil available in USA » Tomatheus, posted by angels78 on September 26, 2010, at 2:37:24
Angels78,
I never felt euphoric on Nardil, just euthymic. On film-coated Nardil, I started to notice some antidepressant benefits at 75 mg, but when I tried putting the contents of the pills into enteric capsules I also responded at 60 mg. I should also add that taking my Nardil in the enteric capsules prolongued my response to the medication beyond two weeks. I know that some people on this site like to refer to the initial effects that they get on Nardil as euphoria or hypomania, and I don't doubt that some people have a euphoric/hypomanic reaction to Nardil, but not everybody experiences euphoria/hypomania on Nardil. Some people have higher levels of the MAO enzymes than others, and it makes perfect sense that what can cause a person with low or average MAO levels to become hypomanic would cause someone with high MAO levels to feel euthymic. A lot of people on this site don't understand this, though. They think that if they experienced euphoria on Nardil that others who take the medication must experience the same thing.
Tomatheus
P.S. I think I weighed around 160 pounds when I was taking Nardil.
Posted by angels78 on September 26, 2010, at 12:42:22
In reply to Re: Have FDA Make Original Nardil available in USA » angels78, posted by Tomatheus on September 26, 2010, at 12:08:41
Did you ever think of gradually increasing your dose to 90, gradually over a month or two months time, and see if it benefited you.
Posted by Tomatheus on September 26, 2010, at 13:14:39
In reply to Re: Have FDA Make Original Nardil available in USA » Tomatheus, posted by angels78 on September 26, 2010, at 12:42:22
I experienced remission at 75 mg at one point, so neither I nor my psychiatrist at the time thought that it would be necessary to increase the dose to 90 mg. I also experienced intolerable back pain when I was taking 75 mg of Pfizer's Nardil, and that prompted me to lower my dose to 60 mg. Increasing the dose to 90 mg probably would have made the back pain worse.
Tomatheus
Posted by ed_uk2010 on September 28, 2010, at 17:30:24
In reply to Have FDA Make Original Nardil available in USA, posted by johneangel on September 21, 2010, at 16:09:07
>the illegal reformulation of Nardil...
The FDA cannot force a company to market a particular product. If the FDA was to decide that the 'new' Nardil was unsatisfactory and needed to be withdrawn, that could leave you with *no* Nardil because the manufacturer wouldn't necessarily decide to start selling the 'old' Nardil again. Instead, the manufacturer may simply discontinue Nardil entirely (as a not very profitable product).
The FDA will already have the details and characteristics of the 'old' Nardil - I'm not sure that they need samples.
Difficult situation.
This is the end of the thread.
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