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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 16 of 16. This is the beginning of the thread.
Posted by bearfan on August 13, 2009, at 21:23:38
Anyone know why the FDA Failed to approve Lexapro for Social Anxiety and Panic Disorder indications? Was the efficacy not there? The studies were a few years ago
Posted by morganator on August 13, 2009, at 22:13:04
In reply to FDA fails Lexapro Approval for Social and Panic, posted by bearfan on August 13, 2009, at 21:23:38
I think Lexapro could be and has been very successful at treating both. The only problem is it may take up to 10 to 12 weeks for the anti-panic and anti-social anxiety effect to be fully felt.
Lexapro is very powerful. For this reason it may be too stimulating in the first few weeks of treatment-not good for SA or PD.
Posted by Phillipa on August 14, 2009, at 0:44:14
In reply to Re: FDA fails Lexapro Approval for Social and Panic, posted by morganator on August 13, 2009, at 22:13:04
I didn't know that if so and quite a few need a benzo for start up anxiety why do the docs prescribe it for anxiety? Thanks Phillipa
Posted by floatingbridge on August 14, 2009, at 1:01:31
In reply to Re: FDA fails Lexapro Approval for Social and Panic, posted by morganator on August 13, 2009, at 22:13:04
Interesting. Lexapro did zip for my social phobia--and I was on it awhile.
fb
Posted by SLS on August 14, 2009, at 6:13:48
In reply to Re: FDA fails Lexapro Approval for Social and Pani » morganator, posted by floatingbridge on August 14, 2009, at 1:01:31
> Interesting. Lexapro did zip for my social phobia--and I was on it awhile.
Do you still suffer from social phobia?
- Scott
Posted by floatingbridge on August 14, 2009, at 12:40:19
In reply to Re: FDA fails Lexapro Approval for Social and Pani » floatingbridge, posted by SLS on August 14, 2009, at 6:13:48
Hi Scott
Well, it depends what side of my dexedrine I'm on, sad to say. It's the only med so far that lifts it. Thanks for asking--
fb
Posted by SLS on August 14, 2009, at 12:50:34
In reply to Re: FDA fails Lexapro Approval for Social and Pani » SLS, posted by floatingbridge on August 14, 2009, at 12:40:19
> Hi Scott
>
> Well, it depends what side of my dexedrine I'm on, sad to say. It's the only med so far that lifts it. Thanks for asking--Frustrating.
Nardil
Paxil
EffexorDid any of those help at all?
- Scott
Posted by floatingbridge on August 14, 2009, at 13:12:16
In reply to Re: FDA fails Lexapro Approval for Social and Pani » floatingbridge, posted by SLS on August 14, 2009, at 12:50:34
> > Hi Scott
> >
> > Well, it depends what side of my dexedrine I'm on, sad to say. It's the only med so far that lifts it. Thanks for asking--
>
> Frustrating.
>
> Nardil
> Paxil
> Effexor
>
> Did any of those help at all?
>
>
> - ScottHi Scott,
Effexor did give me a lift briefly, then pooped. I was on that awhile. Haven't tried paxil or nardil. I have been thinking of parnate or emsam (worried about side effects of nardil). Does paxil give some people relief? Usually SSRI's aren't 'enough'--and have fatigue effects. I've started my pristiq 100 trial and promised to see it to the end or unless my pdoc ends it first (I'm in about 2.5 weeks). Nada so far except more fatigue.
hope today is an okay one for you, if not better,
thanks,
fb
Posted by SLS on August 14, 2009, at 13:40:57
In reply to Re: FDA fails Lexapro Approval for Social and Pani » SLS, posted by floatingbridge on August 14, 2009, at 13:12:16
> > Nardil
> > Paxil
> > Effexor
> >
> > Did any of those help at all?
> Effexor did give me a lift briefly, then pooped. I was on that awhile. Haven't tried paxil or nardil. I have been thinking of parnate or emsam (worried about side effects of nardil).Parnate is the more powerful antidepressant.
When Emsam first came out, it seemed that it possessed anxiolytic properties that appeared very early in treatment. Unfortunately, I haven't spoken to my doctor about the long-term success he has had with his patients. I'll try to remember to ask him the next time I see him.
> Does paxil give some people relief?
Definitely. It is probably the most effective SSRI / SNRI for treating anxiety disorders. It is also the most potent serotonin reuptake inhibitor of the SSRIs.
> Usually SSRI's aren't 'enough'--and have fatigue effects. I've started my pristiq 100 trial and promised to see it to the end or unless my pdoc ends it first (I'm in about 2.5 weeks). Nada so far except more fatigue.
The sort of patience that you are exercising will work in your favor, whether it is for Pristiq or some other drug. I hope it works for you.
> hope today is an okay one for you, if not better,
Thanks. You too.
:-)
- Scott
Posted by floatingbridge on August 14, 2009, at 14:02:37
In reply to Re: FDA fails Lexapro Approval for Social and Pani » floatingbridge, posted by SLS on August 14, 2009, at 13:40:57
Posted by floatingbridge on August 14, 2009, at 14:04:10
In reply to Re: FDA fails Lexapro Approval for Social and Pani (nm) » SLS, posted by floatingbridge on August 14, 2009, at 14:02:37
Thanks! I'll do some poking around about paxil in the meantime.
fb
(The above NM should have been this!)
Posted by morganator on August 14, 2009, at 17:23:05
In reply to FDA fails Lexapro Approval for Social and Panic, posted by bearfan on August 13, 2009, at 21:23:38
Is there a difference between social axiety and social phobia? I feel like many of us have social anxiety but we do not fear going out and doing things. We may even wait tables but have a more difficult time doing it because of out anxiety. We might want to go out all of the time but drink more because of our anxiety.
With social phobia I would expect that people felt anxiety about going out and doing things around other people in anticipation of doing so.
So, maybe there is a difference between social anxiety and social phobia.
3 friends of mine were on or still are on Lexapro and they all found significant relief from social anxiety and phobia.
Posted by floatingbridge on August 14, 2009, at 17:56:38
In reply to Re: FDA fails Lexapro Approval for Social and Panic, posted by morganator on August 14, 2009, at 17:23:05
Hi Morganator,
That's great that your friends found relief. I think there is a diff between the two, esp the subjective intensity. I was diagnosed with SP during my first major depression. Then I did some cbt and it lessened and also my depression improved. So call it social anxiety. But it can still get pretty intense as far as avoidance goes. I fight it all the time (that's the cbt skills). And when I relapse, it rears up horribly as a primary symptom. (BTW, I was the worst waitress! lol.) And I don't drink....
I do think social anxiety exists often as part of any mood disorder, if only because one may be struggling to appear 'normal' and to be feeling alright. S*cks, though. What do you think?
fb
Posted by morganator on August 14, 2009, at 19:02:08
In reply to Re: FDA fails Lexapro Approval for Social and Pani » morganator, posted by floatingbridge on August 14, 2009, at 17:56:38
I think we all have some social anxiety. Very few people are that confident in the way they need to be to not experience some kind of social anxiety in certain situations. I have more to say on this but I am feeling soooo much alone anxiety right now I don't have the brain power to say what I want to. Ugh!
Morgan
Posted by Phillipa on August 14, 2009, at 19:50:16
In reply to Re: FDA fails Lexapro Approval for Social and Pani » floatingbridge, posted by floatingbridge on August 14, 2009, at 14:04:10
fb first ad I was on with low dose xanax and lopressor 25mg. Three months of not feeling well and was better l0mg of paxil. And then returned to RN role and lasted til dumb pdoc decided to try another med what a mistake to go off it. Love Phillipa
Posted by hyperfocus on August 16, 2009, at 18:20:40
In reply to Re: FDA fails Lexapro Approval for Social and Panic, posted by morganator on August 14, 2009, at 17:23:05
> Is there a difference between social axiety and social phobia? I feel like many of us have social anxiety but we do not fear going out and doing things. We may even wait tables but have a more difficult time doing it because of out anxiety. We might want to go out all of the time but drink more because of our anxiety.
>
> With social phobia I would expect that people felt anxiety about going out and doing things around other people in anticipation of doing so.
>
> So, maybe there is a difference between social anxiety and social phobia.
>
> 3 friends of mine were on or still are on Lexapro and they all found significant relief from social anxiety and phobia.I don't know if there's an official clinical difference but when I was younger I had a lot of anxiety in social situations, but I still did them (going out, going to visit friends and so on.) But as I got older my fear became phobic - I really am terrified at the most mundane human contact now. I'm housebound and afraid to even go outside and take out the garbage or walk my dog. The funny things is I actually have much less fear speaking in front of a crowd or making a presentation.
So it seems to me that maybe you could create a gradient with social anxiety on one end, representing a marked increase in anxiety in social situations, and social phobia on the other end representing a different stage where there is a huge amount of fearful anticipation and avoidance. Of course there's also AvPD.
This is the end of the thread.
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