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Dr. Bob is Robert Hsiung, MD,
bob@dr-bob.orgShown: posts 1 to 10 of 10. This is the beginning of the thread.
Posted by SLS on May 13, 2000, at 10:35:16
Hi again.
I am having trouble choosing between sulpiride (Valirem, Dolmatil) and amisulpride (Solian). Amisulpride is so damned expensive.Any comments?
I am interested to know about the quality of antidepressant response, dosage recommendations, side effects, and what other drugs are being taken in combination with either drug.
It would be especially helpful to hear from anyone who has tried both.
I thank you all profusely.
- Scott
Posted by Chris A. on May 13, 2000, at 21:50:01
In reply to Sulpiride vs Amisulpride - Trouble choosing., posted by SLS on May 13, 2000, at 10:35:16
Scott,
Just a commment out of total ignorance, as I know nothing about these drugs. Would it be so bad just to give the less expensive one a trial? Who knows, it just might work. For your sake I hope that whatever you decide to try gives you some relief.Best,
Chris A.
Posted by Chris A. on May 13, 2000, at 23:27:03
In reply to Sulpiride vs Amisulpride - Trouble choosing., posted by SLS on May 13, 2000, at 10:35:16
Would you like for me to ask Karen B. your questions when I talk to her? The Sulpiride reportedly worked well for her. Then again, in unrelated comments she thought I ought to try Amisulpride.
Personally, if a med isn't approved for use in the US I want to know exactly why. Having a mental picture of the med's chemical structure is comforting to me, too.'Night,
Chris A.
Posted by AndrewB on May 14, 2000, at 8:35:32
In reply to Sulpiride vs Amisulpride - Trouble choosing., posted by SLS on May 13, 2000, at 10:35:16
> Hi again.
>
>
> I am having trouble choosing between sulpiride (Valirem, Dolmatil) and amisulpride (Solian). Amisulpride is so damned expensive.
>
Scott,Very good question. I've wondered many times how sulpiride and amisulpride compare to one another. I've emailed an Italian pharmacist with this question and I'll let you know what he says.
I'm having a trial now with Mirapex by itself. It has only been a few days but it seems to be surprisingly effective for me. I'll make a post on this in about ten days.
Someone was kind enough to let me know that application for FDA approval of amisulpride has been pending since '97. Approval may be coming soon.
If you take amisulpride over the longterm it can cost as little as 60 cents/day if your dosage is 50mg.s
Scott, please let me if you find an inexpensive, nonprescription source for sulpiride.
AndrewB
Posted by AndrewB on May 14, 2000, at 22:37:28
In reply to Re: Sulpiride vs Amisulpride - Trouble choosing., posted by AndrewB on May 14, 2000, at 8:35:32
An Italian pharmacist was nice enough to respond back quickly as to whether sulpiride or amisulpride should be used for depression. Both sulpiride and amisulpride are marketed in Italy. Amisulpride is one of the major drugs used for depression in Italy. Sulpiride, however, is mainly used for gastro-enterical disorders caused by depression or ansiotic states, according to the pharmacist. Amisulpride is preferred over sulpiride for depression because it is more effective and it has less side effects. Sulpiride's side effects include dry mouth and sedation.
Posted by SLS on May 15, 2000, at 7:52:26
In reply to Re: Sulpiride vs Amisulpride - Choose amisulpride, posted by AndrewB on May 14, 2000, at 22:37:28
THANKS!!!
> An Italian pharmacist was nice enough to respond back quickly as to whether sulpiride or amisulpride should be used for depression. Both sulpiride and amisulpride are marketed in Italy. Amisulpride is one of the major drugs used for depression in Italy. Sulpiride, however, is mainly used for gastro-enterical disorders caused by depression or ansiotic states, according to the pharmacist. Amisulpride is preferred over sulpiride for depression because it is more effective and it has less side effects. Sulpiride's side effects include dry mouth and sedation.
Dear Andrew,
Your reply is appreciated more than you can know.I spent quite some time cruising the Internet last night trying to find the type of clinical information you have provided here. I had pretty much come up empty. The best I could do was to use Medline to explore some detailed pharmacology to make a best guess. It seems that amisulpride is a bit more selective for DA D2/D3 receptors than is sulpiride. Amisulpride looks better on paper.
Thanks.
Thanks.
Thanks.
- Scott
Posted by JohnL on May 17, 2000, at 3:13:48
In reply to Re: Sulpiride vs Amisulpride - Choose amisulpride, posted by SLS on May 15, 2000, at 7:52:26
> THANKS!!!
>
> > An Italian pharmacist was nice enough to respond back quickly as to whether sulpiride or amisulpride should be used for depression. Both sulpiride and amisulpride are marketed in Italy. Amisulpride is one of the major drugs used for depression in Italy. Sulpiride, however, is mainly used for gastro-enterical disorders caused by depression or ansiotic states, according to the pharmacist. Amisulpride is preferred over sulpiride for depression because it is more effective and it has less side effects. Sulpiride's side effects include dry mouth and sedation.The internet sure can be a wonderful tool, yeah? Imagine that, conversing with an Italian pharmacist. Very cool. It reminds me of the responses I got back from 3 different German pharmacies. I did some serious net searching to find a handful of German pharmacies that looked like maybe they could mailorder Amisulpride to me. The reason was because my previous source--Victoria Apotheke in Switzerland--changed to requiring hardcopy mailed prescriptions. I preferred being able to simply fax the prescription, for reasons I won't mention. I received responses concerning price, prescription method, payment method, and estimated time of delivery from three of them. I faxed my prescription to one of those German pharmacies and had Amisulpride delivered to my mailbox in just 10 days. Thanks to the internet.
More on topic, I don't know anything about Sulpiride. I do however highly recommend Amisulpride to anyone. In my experience it is excellent for depression, anxiety, anhedonia, apathy, and social comfort or social interaction confidence. For me it seemed to work very subtle. I didn't really notice when it kicked in, but it snuck in through the back door in less than 2 weeks. One day I just realized, wow, I'm feeling pretty normal. Side effects for me are practically nill. Amisulpride is a great medication and I sure wish we had it in the USA.
JohnL
Posted by SLS on May 17, 2000, at 7:48:36
In reply to Re: Sulpiride vs Amisulpride - Choose amisulpride, posted by JohnL on May 17, 2000, at 3:13:48
> > THANKS!!!
> >
> > > An Italian pharmacist was nice enough to respond back quickly as to whether sulpiride or amisulpride should be used for depression. Both sulpiride and amisulpride are marketed in Italy. Amisulpride is one of the major drugs used for depression in Italy. Sulpiride, however, is mainly used for gastro-enterical disorders caused by depression or ansiotic states, according to the pharmacist. Amisulpride is preferred over sulpiride for depression because it is more effective and it has less side effects. Sulpiride's side effects include dry mouth and sedation.
>
> The internet sure can be a wonderful tool, yeah? Imagine that, conversing with an Italian pharmacist. Very cool. It reminds me of the responses I got back from 3 different German pharmacies. I did some serious net searching to find a handful of German pharmacies that looked like maybe they could mailorder Amisulpride to me. The reason was because my previous source--Victoria Apotheke in Switzerland--changed to requiring hardcopy mailed prescriptions. I preferred being able to simply fax the prescription, for reasons I won't mention. I received responses concerning price, prescription method, payment method, and estimated time of delivery from three of them. I faxed my prescription to one of those German pharmacies and had Amisulpride delivered to my mailbox in just 10 days. Thanks to the internet.
>
> More on topic, I don't know anything about Sulpiride. I do however highly recommend Amisulpride to anyone. In my experience it is excellent for depression, anxiety, anhedonia, apathy, and social comfort or social interaction confidence. For me it seemed to work very subtle. I didn't really notice when it kicked in, but it snuck in through the back door in less than 2 weeks. One day I just realized, wow, I'm feeling pretty normal. Side effects for me are practically nill. Amisulpride is a great medication and I sure wish we had it in the USA.
> JohnL
Thanks John. I appreciate the input.If you don't mind providing the information, I would really like to know where you are currently getting your supply of amisulpride and adrafinil from.
If you prefer, you can e-mail me directly at:
sl.schofield@worldnet.att.net
Thanks a bunch.
Sincerely,
Scott
P.S. Which antidepressants bind to the serotonin molecule?
Posted by JohnB on May 18, 2000, at 4:12:29
In reply to Re: Sulpiride vs Amisulpride - Choose amisulpride, posted by SLS on May 17, 2000, at 7:48:36
> Thanks John. I appreciate the input.
>
> If you don't mind providing the information, I would really like to know where you are currently getting your supply of amisulpride and adrafinil from.John- Me too. Would love to get that info.
my email: wtssaaa@yahoo.com
Also: Am trying St.J's Wort as augmentor per your advice. So far so good after 5 days.
SLS- If you read this; Hope your doin better. Any meds that are helping you?
Posted by Sigolene on May 19, 2000, at 14:15:27
In reply to Re: Sulpiride vs Amisulpride - Choose amisulpride, posted by SLS on May 17, 2000, at 7:48:36
Hi everyone !
I haven't been here for a long time. But i'm back to give you a good link to very detailed informations on amisulpridehttp://www.pol-it.org/focus13.htm
I hope it helps.
Sigolene
This is the end of the thread.
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