Posted by Brainbeard on May 23, 2010, at 15:43:30 [reposted on May 24, 2010, at 22:42:05 | original URL]
In reply to Re: Also, posted by CrAzYmEd on May 23, 2010, at 12:25:01
A potent 5HT1A-agonist could be a key ingredient in an antidepressant cocktail, as Dr. Stahl has marked out. An (S)SRI, a 5HT2A-antagonist and a 5HT1A-agonist, plus perhaps a D2-antagonist, make for a theoretically ideal antidepressant combo, according to Stahl.
Several potent 5HT1A-agonists never made it onto the market, since they weren't very effective as standalone drugs. I thought we were stuck with Buspar (buspirone). Lisuride could be worth its while when added to the right combo. As a standalone drug, I don't expect it to yield very impressive results. Would be glad to be proven wrong though. Will google this stuff to see if I can get it.
Current meds: 10mg melitracene + 0.5mg flupentixol; sertraline 100mg; amitriptyline 25mg; gabapentin (Neurontin) 300mg; melatonin 0.3mg. PRN: diazepam (Valium) 2.5-5mg.
poster:Brainbeard
thread:948688
URL: http://www.dr-bob.org/babble/neuro/20100223/msgs/948712.html