Posted by SLS on May 19, 2010, at 7:27:00 [reposted on May 20, 2010, at 18:36:23 | original URL]
In reply to Re: Gone with trimipramine, posted by linkadge on May 18, 2010, at 20:35:58
> keep mind mind folks that drugs like mianserin & ritanserin are well established antidepressants with no appreciable affinity for monoamine reuptake.
I might be wrong, but I think ritanserin by itself is not so effective as an antidepressant, although it might make a good augmenter. I doubt that we will ever see it marketed, though. As monotherapy, I don't think there are any indications that it would be appropriate for. I'm all but sure that the patent has expired, and no drug company would want to develop it. As a (non-selective) 5-HT2 receptor antagonist, it might even be effective in treating the negative symptoms of schizophrenia, but would not be a sufficient treatment for the entire symptom cluster.
- ScottThe measure of achievement lies not in how high the mountain,
but in how hard the climb.The measure of success lies only in how high one feels he must
climb to get there.
poster:SLS
thread:948075
URL: http://www.dr-bob.org/babble/neuro/20100223/msgs/948089.html