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Re: Gone with trimipramine » linkadge

Posted by SLS on May 19, 2010, at 7:16:52 [reposted on May 20, 2010, at 18:36:23 | original URL]

In reply to Re: Gone with trimipramine, posted by linkadge on May 18, 2010, at 20:30:50

> The TCA's antidepressant effect is (at least partly) due to interaction with opioid receptors. The TCA's display delta agonist like effects, as well as interaction with kappa receptors.
>
> Linkadge

Thank you very much for the info. I was able to come up with a recent abstract on Medline based upon what you said. I imagine you have seen it already, but just in case you haven't, here is the URL:

http://www.ncbi.nlm.nih.gov/pubmed/19828880

Doesn't kappa stimulation produce dysphoria?


- Scott


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