Posted by desolationrower on May 21, 2009, at 4:36:28
In reply to Re: Please, quick explanation?, posted by g_g_g_unit on May 20, 2009, at 22:29:57
> i don't think i called an agonist did i? anyway, i think i found out the answer to my question: low glutamate activity may just as likely be the result of downregulation - following chronic glutamate overactivity - as a phenomenon in and of itself. in which case the introduction of memantine would be useful, since by putting a cap on glutamate excess, it would allow the receptors to begin to upregulate, thus restoring normal glutamate activity.
> d/r are you taking the drug at the moment? i've been taking it for 10 days, 3 days @ 10mg. so far, so mixed. main problem is the impact it's having on my short-term memory, which is in fact making my attention span worse, though i believe it shows its full benefits re: cognition only following chronic use at a therapeutic dose?
did you read the study i posted? theres some more out there, its more complicated than just receptor up/down regulation.
i went to 20mg and stopped, i didn't notice a strong benefit and since i lost my job needed to save all the $ i could
if you're noticing fogginess i'd say wait that out before you increase the dose again.