Posted by desolationrower on September 3, 2008, at 0:38:36
In reply to Re: Inhibit Reuptake of Ser-Yes, Nor-Yes, but Dop-No?, posted by Fivefires on September 2, 2008, at 2:29:17
> Think understand.
>
> Does methamphetamine permanently damage the travel of dopamine to its target? Is this correct?depends a lot on the dosage. Therepeutic, there is some dispute; abuse, probably. Damage is probably relate to the way and extent dopamine neurons connect to others.
> How about Provigil? What is it doing to dopamine reuptake inhibition?
noone knows. It isn't just blocking dopamine reuptake across the board.
> No one said which, I think we refer to these as hormones right? No one explained what one of these is responsible for feeling happy? I've heard serotonin, but then I heard dopamine.
Well if you want to simplify it (and I mean simplify it A LOT), serotonin is more about serenity/content. Dopamine is more about interest/reward. Keep in mind there are a lot of receptors that have different effects from the same neurotransmitter, and the 'where' in the brain matters a lot. And, what 'happy' means.
> Did I say I was on Provigil? Told pdoc felt couldn't get out of bed w/o it. Still, he wants me to remain on it.
>
> In the past couple days, it has been a thought put in my mind, spoken 'by someone'?, which really never occurred to me.
>
> All this time I've been thinking/saying I'm in a major depressive episode. But, labs are suspicious. Could it have been mono all along, or CFS, or EB?
>
> Will call PCP as the tests Phillipa kindly said were the most important to run for a true thyroid reading don't match what my PCP checked. He didn't mark a mono test either. Hope he'll let me do this via his okay on the phone.
>
> I was sort of 'kidding around' (I must be feeling better!?) When I said, 'why isn't there a drug which targets all, SN&D?'
>
> I'd supposed there'd be followups saying 'there already.'
>
> Now, I'm interested in this new one, not yet approved. Look forward to hearing about it.
>
> Tks, 5f
>Hope you find something that works.
-D/R
poster:desolationrower
thread:849657
URL: http://www.dr-bob.org/babble/neuro/20080706/msgs/850016.html