Posted by SLS on September 1, 2008, at 13:49:01
In reply to Re: Inhibit Reuptake of Ser-Yes, Nor-Yes, but Dop-No?, posted by desolationrower on September 1, 2008, at 11:27:20
> I would not worry about 'covering all three neurotransmitters' per se.
So, is it your belief that we don't need a DARI because drugs that address dopamine already exist, despite their not being of the same pharmacodynamic?
Have you ever tried nomifensine to compare it to d-amphetamine, methylphenidate, and bromocriptine? I have. I think that gives me a unique position from which to comment on the desirability of having DARIs become available.
If you don't need a DARI, then you don't have to try one when they come out. But why argue for excluding a drug from our pharmacopia if it is safe and effective? Why argue for less when more is needed? Actually, we will be seeing triple-reuptake inhibitors before too long as at least two are well along into phase II clinical trials.
- Scott
poster:SLS
thread:849657
URL: http://www.dr-bob.org/babble/neuro/20080706/msgs/849732.html