Posted by casse on December 20, 2009, at 17:00:39
In reply to ldn for autoimmune, perhaps with depression?, posted by tealady on February 3, 2009, at 6:18:10
I tried LDN for treating depression and had mixed results. At first it seemed to help, but within days I started feeling worse as anxiety increased. There is some speculation that it sequesters in tissue in some people and that the accumulation causes constant blockade of endorphin production instead of the intermitent blockade which stimulates overcompensation.
A common complaint/side effect of naltrexone at the 50+ mg. used for opiate/alcohol dependence is anxiety. If it is sequestering in tissue even at a low dose, that would explain why I at first felt good on it, but then started feeling worse. Of course, this is speculative.
I was taking btw 1.5 -2.5 mg. One amazing result of taking it was that I didn't get the severe reaction to poison ivy that I usually experience every time I get near it (think being unrecognizable bc facial skin thickens and gets inflamed ). I mowed through fields of it this past summer while on LDN and never got more than a few blistery bumps. Amazing stuff.
The general concensus is that 1.5 ml is the minimally efficacious dose. That is not necessarily true, and in fact, some people claim to be having success starting at much lower doses (.25 ml ) and using LDN only every other or every third day. A few of these people are chemically sensitive.
I don't know if it's ok to post a link to another group site, so I wont, but there is a yahoo group which deals specifically with very low dose naltrexone. It's a relatively new group.
I'm going to start back on LDN after I give tianaptine a go. I know of someone else who uses them concurrently with wonderful results.
poster:casse
thread:877763
URL: http://www.dr-bob.org/babble/alter/20091202/msgs/930031.html