Posted by tealady on February 4, 2009, at 15:33:37
In reply to Re: ldn for autoimmune, perhaps with depression?, posted by Jimmyboy on February 4, 2009, at 10:21:32
Hi again Jimmyboy,
OOps, Apologies. Ignore my last comment on endorphins. I just followed up one of the links in my post.It looks like endorphins do last as long as you say..I guess they just seem to get used up pretty fast in me!
Also some there are no longer taking it at night due to disturbed sleep as you had and are fine in the day. There was a change of thought of what was happening, but again.. don't ask me to explain as I still don't quite have my old brain function back :-)
Maybe worthwhile researching & considering if it may work as effectively taken during the day for you?http://www.ahsta.com/LinkClick.aspx?fileticket=NHtaMiGeHgg%3d&tabid=175&mid=686
"sexual intercourse, eating chocolate and exercise. Because the effects of endorphins are diminished during the opiate receptor blockade, Dr. Bihari originally proposed that LDN be taken at night.
LDN Timeframe
Studies show that the effects of endogenous opiates last from 24-72 hours. Therefore, taking LDN at night is not necessary. A 4.5 mg dose of naltrexone blocks the opiate receptor for about 6 hours. After this temporary blockade, endogenous opiate production increases dramatically.
Increased Endogenous Opiates
Its suspected that the primary effects of LDN are related to the increased production of endogenous opiates. Endogenous opiates include endorphins, enkephalins, and metenkephalins. These compounds act as neurotransmitters and as cytokines. Cytokines are chemicals that modulate the immune response"best wishes and thanks,
Jan
poster:tealady
thread:877763
URL: http://www.dr-bob.org/babble/alter/20090204/msgs/877997.html