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Cholesterol metabolism ? Lar » raybakes

Posted by tealady on October 29, 2004, at 21:19:47

In reply to Re: Do conversions along pathways go both ways? » tealady, posted by raybakes on October 29, 2004, at 7:24:34

OK I looked up what is needed maybe in the pathways
http://www.genome.jp/kegg/pathway/map/map00140.html
"AND CLICKING on 1.14.15.6
Oxidoreductases
Acting on paired donors with incorporation of molecular oxygen
With a reduced iron-sulfur protein as one donor, and incorporation
of one atom of oxygen"

so as well oxygen maybe I need iron-sulfur...there's that sulfur again!!!! (and iron)

OK so for sulfur I need TMG, NAC, NAG ??
I guess something like magnesium sulfate is different?? I have epsom salt baths but they always make me very tired after..actually usually drift in and out of sleep in the bath. Note sure if that's the sulfates or just the relaxation.


Lar mentioned sulfur stuff to me last year too re thyroid hormones.

Another cholesterol path
http://www.genome.jp/kegg/pathway/map/map00120.html
needs that NADPH again and oxygen
"With NADH or NADPH as one donor, and incorporation of one atom of
oxygen"


I thought that CoQ10 (ubiquinone) should be somewhere around cholesterol too? as the drugs that inhibit cholesterol synthesis also stop CoQ10 synthesis? But I can't find the link there.

Jan


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URL: http://www.dr-bob.org/babble/alter/20041022/msgs/408922.html