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Re: Selegiline Phenylalanine

Posted by jboud24 on October 20, 2004, at 0:37:47

In reply to Re: Selegiline Phenylalanine » jboud24, posted by Larry Hoover on October 19, 2004, at 16:13:29

I cant find a ref to back up my assertion and I've spent over 2 hours looking for where I found those numbers at. But despite that, I definitely recall seeing those two numbers and being like wow, because remeron is a medication I do take. I remember thinking to myself, "They (organon pharma) should really market this stuff as an anti-histamine." It totally alleviated my own allergy to cats, which was amazing for me.

But that ki database you found was amazing. However, it lists 4 different values for doxepin's binding to the human H-1 receptor: .09, .16, .32, and .49 nm.
For Remeron, the only value listed was .508, but that was for a rat brain. Too bad they don't have info on binding to the human brain.

Anyways, good site, sorry I cant get the ref.

Justin


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URL: http://www.dr-bob.org/babble/alter/20040928/msgs/404989.html