Posted by chemist on June 19, 2004, at 3:27:39
In reply to GABA, posted by Questionmark on June 16, 2004, at 8:45:22
hello there, chemist here... lar is spot-on. the entire question is quite moot, really: gamma butyric acid is water-soluble and lipid soluble, so crossing the BBB is not an issue. what is an issue is activating the GABA_{A} receptor and inducing chloride flux. if you take GABA and it works - as lar has said - then great. otherwise, there really is no need to go for it, as your GABA_A} (mostly) receptor needs to be inhibited by reuptake, so any additional flooding is not going to help unless you have a drug in the binding site that will inhibit...all the best, chemist
poster:chemist
thread:357170
URL: http://www.dr-bob.org/babble/alter/20040613/msgs/358028.html