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Re: do neuroleptics always=dysphoria?

Posted by linkadge on April 27, 2021, at 11:14:27

In reply to Re: do neuroleptics always=dysphoria?, posted by undopaminergic on April 26, 2021, at 0:09:27

>I'd say the former is more important. Ie. the >anticipation of pleasure is more important than >the pleasure itself, because it produces >motivation, thus counteracting apathy, which is >worse than anhedonia.

True. But there are certainly millions (if not billions) of highly motivated people on this planet, on a continual hunt for peace / pleasure that they never receive. While motivation is important, I also think it is possible to be satisfied without being hypermotivated.

Crudely speaking, hypermotivated people may have a relative dominance of dopamine to serotonin. These are the people who work their *ss*s off to achieve things that they only enjoy for a few sections. For society, this is the 'ideal' type of human, but on an individual level, I don't envy a life of constant treadmill running.

>I'd also say some dopamine receptors are very >close to producing pleasure. Pramipexole was >the only anti-anhedonic drug I tried; it's a >D3>D2 receptor agonist.

Very true. I don't fully understand it myself. However, for some individuals, blocking dopamine might help achieve a better monoamine balance.

Linkadge


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