Psycho-Babble Medication | about biological treatments | Framed
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Re: do neuroleptics always=dysphoria?

Posted by undopaminergic on April 26, 2021, at 0:09:27

In reply to Re: do neuroleptics always=dysphoria?, posted by linkadge on April 25, 2021, at 18:08:22

> No. I personally don't mind a low dose of seroquel or zyprexa. I don't get any major dysphoria at low doses.
> Dopamine isn't the magic pleasure chemical. Dopamine creates 'wanting' and motivation to achieve a reward, but it doesn't always produce reward in itself.

I'd say the former is more important. Ie. the anticipation of pleasure is more important than the pleasure itself, because it produces motivation, thus counteracting apathy, which is worse than anhedonia.

I'd also say some dopamine receptors are very close to producing pleasure. Pramipexole was the only anti-anhedonic drug I tried; it's a D3>D2 receptor agonist.





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