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Maybe Doses are Too High?

Posted by bleauberry on December 29, 2018, at 8:34:29

So this is just armchair theory. Just thinking out loud....

I was studying up on CBD oil. I learned that the oil weakly binds to the CBD1 and CBD2 receptors. Those are attached to all sorts of stuff involving mood, temperature, immune system and the opioid system.

In that weak binding CBD oil acts as both an agonist and an antagonist. It is described as "brushing" the receptors, with the end result being that it causes an increase of natural opioid production similar to how Low Dose Naltrexone does, and also helps existing opioids and neurotransmitters as a weak agonist of them.

From a consensus point of view some of the primary benefits people claim from CBD oil are anti-anxiety, anti-insomnia, anti-pain and anti-depression.

So I couldn't help but wonder, what if we dosed something like Prozac so lightly that it just brushed the receptors? So that it could in a sense excite the neurons with a little extra serotonin but not flood them? To just lightly touch them and lightly block them at the same time? Instead of overwhelming with a totally unnatural flood?

Or any med. Lightly brush the receptors with a tiny bit of Zoloft, Zyprexa, whatever. To get some of their mechanism, but only some. A totally different approach.

Maybe my first lyme doc was onto something when he said he had patients doing well on 1mg of Lexapro....

Heck I remember he started me on Lexapro at just one drop, which was 1/10th of 1mg, and I actually felt it. I hated Lexapro and wanted nothing to do with it and had already been there done that, so eventually had to find another doc. But the point was, he had found super-light dosing of psychiatric meds to work better than conventional dosing.

Just thinking out loud....


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poster:bleauberry thread:1102639
URL: http://www.dr-bob.org/babble/20181024/msgs/1102639.html