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Re: Nardil update. Escapee

Posted by SLS on September 24, 2016, at 9:27:27

In reply to Re: Nardil update. SLS, posted by Escapee on September 24, 2016, at 8:44:00

I would not use the every-other-day dosing strategy with Nardil. I've been there.

The half-life of Nardil is only 12 hours. You would be surprised just how quickly Nardil withdrawal sets in. MAO inhibition is not the only thing that Nardil does. I can't go 48 hours without suffering a change in dreaming and feeling less well. I think some of this is the loss of MAO inhibition. Some of it may be a loss of GABA transaminase inhibition. Some is probably the loss of some sort of stimulant effect that has not yet been investigated. Again, I would just break the 15 mg tablets in half, one tablet at a time as needed. Each 1/2 tablet should remain 100% effective - certainly after standing for only 24 hours. I have had doctors do this with me, especially when Nardil was to be added to a TCA. In addition, it is my guess that skipping days will not allow the body to acclimate itself to Nardil. Pulsing the dosage might make side effects worse or slower to abate.

It is just something to think about.

- Scott

Some see things as they are and ask why.
I dream of things that never were and ask why not.

- George Bernard Shaw




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