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Re: Started Nardil SLS

Posted by Escapee on August 27, 2016, at 11:09:56

In reply to Re: Started Nardil Escapee, posted by SLS on August 27, 2016, at 9:22:24

> > I'm just glad I'm back on Nardil. I wonder what will happen.....
>
> I am sure you know that Nardil often becomes less effective once it is discontinued and restarted. If this is the case with you, I wouldn't become too demoralized. This is what happened to me. There are multiple augmentation strategies that are available to treat this circumstance. First things first. I don't think it makes sense to add anything to phenelzine until you reach a dosage of 1.0 mg/kg body weight.
>
>
> - Scott

You are right Scott. But one can only hope. It has been over 12yrs tho.

Biggest mistake ever made was coming off Nardil, at the time at least. I realized it never actually stopped working as once stopped my SA soared thru the roof. But the depression was stubborn. But compared to the Isocarb I only tried a few addons/augmentations with Phenelzine- modafinil, trimipramine, L-tryptophan (Optimax), bupropion, lamotrigine... My doc at the time had said he'd read of a study done using sertraline to augment phenelzine. It was offered to me, but he said he'd given it to one other patient who suffered 'annoying' side effects tho nothing serious. Anyway I declined, but remembered.

Most augmentations tried with Isocarb were never tried with Phenelzine. I'm surprised he wanted me to stay on all other meds whilst cross titrating. Maybe coz he is cautious of my sometimes stubborn depression.

Quetiapine fine, may even help prevent mood swings which I experienced 1st time round on phenelzine. From really outgoing to curtains drawn teary gloomy with little explanation, only to perk up again the next day. I thought maybe it was short-lived med-induced Bipolar? Doc said it wasn't.

I'm far from hoping for a miracle, but optimistic nonetheless. I know my docs fine to take it to 120mg if necessary.

Mind you my docs most familiar with tranylcypromine (Parnate) than any of the other MAOIs. So that's a pretty good safety net I'd say. The combinations are seemingly endless between the 3 irreversible MAOIs & addons/augmenters which would shock most GPs and others a-like.

I'm surprised to see you follow the 1mg per kg weight rule. I dont buy it. And the patients info slip STILL says a maintenance dose of as low as one tablet (15mg) every other day. What is that about and why does it still appear on the slip when the slip also states: last revised on 04/2015! I mean, was that how they used to, or still do (some doctors) prescribe it successfully?
The food interactions are still totally outdated too! Don't eat yogurt??? I eat a 450ml pot of live yogurt every day.
Craziness.

Escapee


Amitriptyline 100mg
Bupropion 300mg
Quetiapine 150mg
Clonazepam 2.5mg
Pregablin 400mg
Phenelzine (Nardil) 15mg increase to 45mg


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poster:Escapee thread:1091031
URL: http://www.dr-bob.org/babble/20160819/msgs/1091566.html