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Re: Anyone's taking Agomelatine (Valdoxan)? » SLS

Posted by Hana on September 19, 2016, at 6:23:22

In reply to Re: Anyone's taking Agomelatine (Valdoxan)? » Hana, posted by SLS on September 18, 2016, at 15:18:43

> > > > Looks like Valdoxan is a mild drug. I'll look into something else. Btw that new treatment looks great. Is it availbale now or not yet?
>
> > > I have a severe anergic bipolar depression with anhedonia and cognitive impairments. I take a combination of antidepressants, mood stabilizers, and an antipsychotic with antidepressant properties. I tried switching from Abilify to Vraylar. It made me feel much worse. I am currently switching to Reluxti. So far, I am feeling better than I was on Abilify. I am very much encouraged that I will continue to improve.
> > >
> > > Currently:
> > >
> > > Parnate 80 mg/day
> > > nortriptyline 150 mg/day
> > > Lamictal 300 mg/day
> > > lithium 300 mg/day
> > > Reluxti 1.0 mg/day
> > > prazosin 30 mg/day
>
> > Sounds great! gonna suggest Reluxti to my pdoc. How long have you been on it? Are there any SEs especially in regards to sex drive?
>
> I have been taking Reluxti for about two weeks. I noticed a positive response by day 7 at a dosage of 1.0 mg/day. In my experience, when trying an atypical AP to treat depression, I feel an improvement within a week, provided the dosage is high enough. With Reluxti, you start at 0.5 mg/day for 7 days, then 1.0 mg/day thereafter. I haven't been able to evaluate Reluxti for sexual side effects, as I take prazosin, which can reduce libido drastically. I will have to let you know about weight gain in the coming weeks. I still take 7.5 of Abilify, which I am still tapering. Reluxti is supposed to be more tolerable than Abilify if akathisia is an issue. I felt a little "drugged" for the first few days, but this sedation-like feeling disappeared completely. I will know more about the trajectory of my response to Reluxti over the next few weeks. I hope it doesn't plateau. It will be very demoralizing if I get "stuck" again.
>
> I wish you the best.
>
>
> - Scott
>
I'm glad it works for you. I hope it won't cause any sexual side effects. Having a normal sex drive is important for me. Take care :)


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poster:Hana thread:1092111
URL: http://www.dr-bob.org/babble/20160819/msgs/1092255.html