Posted by Louisiana Sportsman on July 4, 2015, at 10:43:56
In reply to Re: Thinking of Tweaking My Combo. Thoughts Please?, posted by Louisiana Sportsman on June 20, 2015, at 15:09:46
I decided to minimize as much as possible. I'm off the Remeron completely and the Latuda and reduced my Topamax to 200mg. per SLS' suggestion. I'm also taking less supplements, no more valerianr root and things I can get from a multivitamin; so at the present, I am taking:
Pristiq 50mg. QD
Wellbutrin XL 300mg. QD
Topamax 100mg. BID not TID anymore total 200mg.
Gabapentin 600mg. QID total 2,400mg.
NAC 600mg. QID same time as I take the gabapentin total 2,400mg.
Fish Oil DHA/EPA 960mg. QD (haven't even taken this a month straight to assess benefit yet, almost have taken NAC for a month with no side effects for both fish oil and NAC)
Multivitamin
Melatonin 3mg. QHS
Prilosec 40mg. CFI'm in remission, I believe of MDD/GAD with this cocktail that is working for me. I've been in and out of PDOC offices and this is the best I've come up with in awhile.
Trying to treat a possible glutamate-GABA imbalance with high dose NAC/gabapentin since most neurotransmitters are GLU/GABA. GABA-B, which gabapentin acts on, is indicated in MDD. Wellbutrin XL now without the Latuda is giving me some dopaminergic action, and it is working hand-in-hand with Pristiq's effect on NE. Pristiq is a good maintenance medicine for my MDD. Topamax is somewhat effective to ameliorate my binge eating disorder, mood instability and substance abuse liability.
Going off the Remeron has given me some increased energy, and I think I'm doing better without it in regards to my weight. Also I'm not bipolar, but my previous dx was bipolar depression; therefore, Latuda was indicated. I really don't need dopaminergic antagonism in my life right now and going off of it has not exacerbated my depressive symptoms.
I will get retested for ADHD sometime in the future and be put on something for it, but I'm not sure what it will be. But, in terms of my non-ADHD symptoms, they are being treated as best as I think they can. The only thing I'm thinking about adding will be nootropics/supplements, but I'm going to assess this regimen first.
Thanks for the advice given in this thread. If anyone has any thoughts, please, please share I'd love to hear from you!
poster:Louisiana Sportsman
thread:1079762
URL: http://www.dr-bob.org/babble/20150629/msgs/1080213.html