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Re: Replay: High cortisol = poor response to Prozac » miko84

Posted by SLS on June 16, 2015, at 6:43:13

In reply to Re: Replay: High cortisol = poor response to Prozac, posted by miko84 on June 16, 2015, at 5:20:53

> Yes, it's true - serotonergic antidepressants can increase activity of HPA axis via 5-HT1a, 5-HT2a/c and 5-HT3 activation. All 5-HT2a/c antagonist are good for lowering cortisol.
>
> That's why SSRI's are not so good in depressions with high cortisol. Mirtazapine/amitriptiline/olanzapine/quetiapine and other antipsychotics are better for that.

Thanks, Miko84.

I didn't know any of that.


- Scott


Some see things as they are and ask why.
I dream of things that never were and ask why not.

- George Bernard Shaw

 

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