Posted by miko84 on June 16, 2015, at 5:20:53
In reply to Re: Replay: High cortisol = poor response to Prozac, posted by linkadge on June 7, 2015, at 12:04:17
Yes, it's true - serotonergic antidepressants can increase activity of HPA axis via 5-HT1a, 5-HT2a/c and 5-HT3 activation. All 5-HT2a/c antagonist are good for lowering cortisol.
That's why SSRI's are not so good in depressions with high cortisol. Mirtazapine/amitriptiline/olanzapine/quetiapine and other antipsychotics are better for that.
poster:miko84
thread:1079501
URL: http://www.dr-bob.org/babble/20150520/msgs/1079790.html