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Re: Starting Parnate after 15 yrs treatment-resistance

Posted by Robert_Burton_1621 on February 9, 2015, at 8:00:35

In reply to Re: Starting Parnate after 15 yrs treatment-resistance, posted by rjlockhart37 on February 5, 2015, at 15:07:02

> Parnate has always been known for treatment resistant success over other antidepressants, it is VARY effective in any type of depression, just side effects are a bit more.....>

> there's also Nardil and Marplan if parnate doenst do the trick.....>

> try to get the dose up maybe see if it works,>

Thanks for this reassuring info. Parnate's effectiveness in "treatment-resistant" cases is one reason why I've pursued it. The often-cited Star*D trials which examined sequenced medication alternatives to treat chronic (or persistent) depressions reached the contrary conclusion: but this putatively authoratative contrariety is, it seems,owing substantially, perhaps exclusively, to flawed method: the median dose of parnate in the study was only 39mg, I think.

My psychiatrist's preference is Nardil, as it happens. I thought it most prudent to try Parnate first, given it is reputed to have less side-effects than phenelzine. This is the course suggested by Dr Gillman on his site, too, and it seems logical to me.




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