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Re: Cymbalta vs Pristiq » Beckett

Posted by klein on April 29, 2014, at 9:58:13

In reply to Re: Cymbalta vs Pristiq » klein, posted by Beckett on April 28, 2014, at 14:24:52

> Did you come to a decision yet? Having been on both effexor and Pristiq, it is true that there are far less side effects with Pristiq. It was mildly activating, although for me, it destabilized my mood. But if I recall correctly, that is not an issue for you. Cymbalta was good in many ways except I had a side effect which required me to discontinue (GI pain). Fwiw, heavy NE hitters make me drowsy and even worsen my pain condition (strattera) though I think that is an atypical response. Cymbalta was the exception, and I wished I could tolerate it. Welcome, btw.

Hi B,
Yeah, we decided to try Pristiq 100mg and upped the Zoloft to 300. We chose Pristiq because I have the same reaction to NE hitters as you, they send me right off to sleep! So Pristiq seemed like the best option (high dose Zoloft is also helping).

We've discussed Savella and Fetzima in your thread, they're big on NE but I still think you should consider giving them try.

I'm becoming increasingly convinced that I have some sort of ADHD disorder (or whatever it's called) and could benefit from taking stimulants. So today I contacted my health insurance and asked to see another pdoc to get a second opinion, as my current one flat out refuses to prescribe amphetamines (for no good reason, I've never abused any of the meds he's given me)

I'm 100% unipolar.

Thanks for the welcome =)

Warm regards,
k
oh ps. about your GI problems with Cymbalta. I used to have GI *distress* on Zoloft (won't go into the gory details) so after a few weeks, I switched to another SSRI for a while. Then I switched back to Zoloft and the GI problems were much more manageable and they're gone now. It's like the previous med "prepared" me or desensitized me more gently for Zoloft's harsh GI side effects. If Cymbalta worked so well for you, maybe you can come up with a similar strategy.


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