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Re: Cymbalta vs Pristiq » jono_in_adelaide

Posted by klein on April 23, 2014, at 19:31:46

In reply to Re: Cymbalta vs Pristiq, posted by jono_in_adelaide on April 23, 2014, at 18:24:11

Thanks for replying, Jono.

I tried Wellbutrin XL at 300 with the Zoloft some time ago; the combination worked nicely for a while with no additional side effects, but after a few months it lost effectiveness (started to make me very sleepy, just like Savella and Provigil).

Wellbutrin SR might be an option though, I tried it alone ages ago and it was definitely very activating.

I wouldn't mind losing the Zoloft altogether. My doc won't prescribe my optimal sertraline dose because it's higher than the usual recommended max dose. Even though there are several studies in Pubmed which demonstrate the safety of long-term treatments well in excess of 200mg, my pdoc won't have it.

I don't protest too much because the higher doses of Z. don't bring about remission, but just a bit of extra relief. While it lasted, 50mg Zoloft + 225 Effexor was better than 300+mg Zoloft alone.

> I'd suggest combining Zoloft at whatever dose worked for you with Welbutrin XL 300mg in hte morning.
>
> Try this for a month and see how you feel after 4 weeks.


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