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Re: How can the half-life of Marplan be unknown? SLS?

Posted by tom2228 on March 31, 2014, at 15:01:52

In reply to Re: How can the half-life of Marplan be unknown? SLS?, posted by PeterMartin on March 31, 2014, at 13:51:45

> Wow that was great! Thanks!
> How did you settle at 50mg? Did you try 40mg for a while and step up or were you quick to reach that dose and just stick with it?
> Can I also ask when you take it? Divided doses?
> Thanks!!

No problem, I have sort of a vested interest in Marplan. I am no longer taking it, but it's done a lot for me over the years. I just washed out and am starting notriptyline tonight because my new pdoc didn't have the guts to combine the two and depression had gotten much worse.

I actually started at 20mg and stayed for about 3/4 year, then I got up to 30mg at a rehab when I recognized my leftover dysthymia was related to my use of drugs. A year later in a major depressive episode I went up to 40mg. I did well for another year and was taken off Marplan when incarcerated. I then trialed Nardil and retrialed Parnate. I was unhappy with the results and wished to return to Marplan.

Having put a lot of effort and time into my recovery from substance use at this point and with a clearer perspective on the severity of my mental health, my expectations for antidepressive treatment had changed. I realized I had been accepting sub-par symptom coverage because it had been the best coverage I had had before and simply didn't know any better. I recognized the importance of trying to achieve full remission and decided to aim for 50mg.

I always took it twice a day. The latest was 30mg in the morning and 20mg at 2pm.




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