Posted by SLS on December 20, 2013, at 14:23:05
In reply to Re: Amisulpride plus Pramipexole?, posted by uncouth on December 20, 2013, at 12:43:58
Uncouth...
Before I forget, it is critical to understand that a good portion of amisulpride's antidepressant effect might be mediated through serotonin 5-HT7 receptor antagonism. It is a very potent drug at this receptor. Two other neuroleptic antipsychotic drugs that are also potent 5-HT7 receptor antagonists are risperidone (Risperdal; Invega) and lurasidone (Latuda). Do not overlook lurasidone. It might go well with a more DA/NE antidepressant like bupropion (Wellbutrin).
Just a thought.
- ScottSome see things as they are and ask why.
I dream of things that never were and ask why not.- George Bernard Shaw
poster:SLS
thread:1056502
URL: http://www.dr-bob.org/babble/20131209/msgs/1056620.html