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Re: Nortriptyline and my ADHD/ADD? » SLS

Posted by doxogenic boy on October 13, 2013, at 5:08:14

In reply to Re: Nortriptyline and my ADHD/ADD? » Psycho316, posted by SLS on October 12, 2013, at 13:37:43

> The dosage range for nortriptyline when used to treat depression is generally 75 - 150 mg/day.

When I used nortriptyline, I got over the therapeutic window with doses higher than 50 mg, but I am a slow metabolizer. When I used 150 mg, I got more than 3-fold over the therapeutic window and I felt crappy. 50 mg worked. So it is important to take blood tests, if there are too much side effects or lack of effect. Too high doses work just as bad as too low for this medicine.

http://www.nlm.nih.gov/medlineplus/ency/article/003430.htm

Therapeutic window for nortriptyline: 50 to 150 ng/mL

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2816343/

Quote from the link above:
However, steady-state concentrations in plasma observed in the course of treatment with TCAs are poorly related to the administered dose, and values in patients who were given similar doses of TCAs can vary from 10- to 35- fold


Earlier TRD/anxiety
300 mg tianeptine, 6 X 50 mg successfully since Oct 2009
20 mcg liothyronine
40 mg escitalopram
100 mg trimipramine
50 mg agomelatine
600 mg quetiapine


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