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Re: Does Apathy Ever Go Away? » SLS

Posted by Hugh on July 13, 2013, at 10:21:21

In reply to Re: Does Apathy Ever Go Away? » Hugh, posted by SLS on July 4, 2013, at 4:56:02

> Do you think that you would respond to baclofen were you to restart it?

The dose that had the remarkable antidepressant, anti-anxiety effect on me was 75-100 mg. But after a week on this dose, I couldn't sleep anymore. I was up for over fifty hours straight when I decided to stop taking it. After it cleared my system and I could sleep again, I started taking it again, and slowly increased my dose over the next few weeks. I got up to 37.5 mg when it started to aggravate my mitral valve prolapse. It wasn't helping my depression or anxiety at this dose, so I decided to abandon it. But I'm extremely sensitive to many drugs and supplements. I think most people could tolerate those doses of baclofen without those side effects. Baclofen increases striatal levels of dopamine. Maybe that's why it worked so well for me, for a while, and why it caused insomnia.


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