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Re: Ketamine and side effects brynb

Posted by jrbecker76 on February 18, 2013, at 22:04:09

In reply to Ketamine and side effects, posted by brynb on February 18, 2013, at 15:32:35

> Is anyone aware of common side effects w/ Ketamine treatment?
> Has anyone experienced side effects with Ketamine treatment? And, is it supposed to help or aggravate irritability?
> Thanks,
> b

Hi Bryn,

I'd also be curious to hear what Dr. Fruitman says about this in his experience with other patients.

As I mentioned in another thread, irritability was listed as a minor SE in a couple studies I read related to ketamine tx for bipolar depression. But only a couple of subjects experienced it though. I can email you those studies if you'd like.

As a side note, I was in a clinical trial for a new glutamatergic antidepressant drug (mGlu 2/3 antagonist). I experienced both headaches and irritability as side effects. Generally speaking, I am sensitive to most antidepressants in regards to causing irritability though.

Just to reiterate for those not following the last thread, you remarked that you've struggled with irritability prior to initiating treatment but that it has been made worse by the ketamine injections. In terms of the enhanced irritability after the infusions, does it eventually abate/fade or do you find yourself with it for the next few days or week and beyond?

You also mentioned that you have some baseline cognitive dysfunction. I'm wondering if you have noticed an increase in disorganized thought, word recall, attention, or memory (aside from the first few hours after an injection) now that you've had a few more treatments under your belt.

Lastly, would you say ketamine is beneficial or detrimental for anxiety alone?

I hope that the next few weeks of treatment will work out the kinks for you.





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