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Re: Modafinil Issues Ugh. Also need help w Memory!! » AlexCanada

Posted by phidippus on September 7, 2012, at 16:36:44

In reply to Modafinil Issues Ugh. Also need help w Memory!! » SLS, posted by AlexCanada on September 7, 2012, at 4:24:31

Less far along in the development pipeline is Memory Pharmaceuticals' experimental drug, MEM 1414. It's currently in phase I trials, which are designed to test safety in people.

MEM 1414 works by blocking phosphodiesterase, an enzyme that breaks down an important brain chemical, cyclic AMP. It appears to work in the area of the brain where new memories are formed. "It's very important for facts and events," says Axel Unterbeck, PhD, president and chief scientific officer of Memory Pharmaceuticals.

"In order to be able to form new long-term memories -- which are memories lasting for more than three hours, by definition ... the [brain] also processes that information for facts and events to be stored long term, he says. "If you enhance this pathway, you get, potentially, enhancement of this very function."


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