Posted by AlexCanada on August 17, 2012, at 21:29:58
In reply to Re: Severe Melancholic. My story. Please help. » AlexCanada, posted by SLS on August 16, 2012, at 7:38:38
I feel worse early in the day. Mornings can vary depending on my sleep schedule. Usually I feel worse after waking but also early afternoon. Evenings I tend to feel a bit better and middle of the night often feel even better. Also I notice I feel usually worse during the hours after parnate doses. But much of that might be the sedation.
I used to wake up quite early in the mornings. My sleep is a bit inconsistent and depends on my current meds. a few weeks ago I def kept waking up really early such as 3am. When I was on just ritalin and low dose valium I would often sleep a lot without waking for many hours.
Psychomotor retardation... absolutely. Often extremely limited ability to think, slow through process, thoughts can be cut off abruptly, can forget what I was just thinking about, often difficult to construct intelligent sentences and then I notice idiotic mistaks afterwards, feel extremely intellectually compromised, slow thinking, indecisive at times, difficult to speak intelligently and be able to properly articulate myself, often extremely poor imagination except during night time, long term memory problems, severe antero grade memory loss (difficult retaining new information), sluggish, slowed speech, and sometimes very difficult to comprehend and process information, sometimes difficult to even read. I often feel that something is ''blocked'' and I just can't think...
Do not feel there is aggitation.
I have tried lithium before, it may have been with paxil. it didn't seem to do much of anything and i believe i felt more sluggish. possibly my dose was too high. i don't remember.
The lithium... do you recommend it on it's own (with valium + ritalin) or as an add-on to an anti-dep?
What is T3?
And Imipramine/Clomipramine are they known for cognitive impairment on the same or similar severity compared to other anti-deps? But... if they can work for melancholic then my cognitive issues could be very much alleviated regardless.
Just not sure what is left but pristiq, imi/clom and possibly a TCA...
Rhodiola worked better when I was not on parnate. They likely don't mix well. I may try Rhod with a dif class med.
> Some people respond to imipramine or clomipramine who do not respond to nortriptyline.
>
> Do you feel worse in the morning?
>
> Do you experience early morning awakenings?
>
> Do you have psychomotor retardation? How would you describe it?
>
> Do you experience aggitation? How would you describe it?
>
> Don't forget about lithium and T3 as augmenters of tricyclics. I would try the lithium first. People sometimes respond within a few days at a relatively low dosage.
>
> You did a good job detailing your response pattern to different treatments.
>
>
> - Scott
poster:AlexCanada
thread:1023380
URL: http://www.dr-bob.org/babble/20120803/msgs/1023566.html