Posted by SLS on February 26, 2012, at 12:55:35
In reply to Re: med strongest on serotonin, posted by Laney on February 26, 2012, at 12:05:57
> Could it be said that the stronger the SSRI, the worse the Withdrawl? Think about it Paxil, Effexor Cybalta all typically have a bad withdrawl associated with them.
>
> Laney
That's great thinking.:-)
I really don't know.
Effexor is not nearly as potent as Paxil or Cymbalta at the serotonin transporter. You've got me curious now. I had thought that perhaps having a short half-life was contributory to a drug having a more severe withdrawal syndrome. I'm thinking that there should be more to it than that. Maybe NE or ACh? But, then you would think that clomipramine (Anafranil) would be just as bad as Paxil. It isn't.
I bet Linkadge could figure it out.
- Scott
Some see things as they are and ask why.
I dream of things that never were and ask why not.- George Bernard Shaw
poster:SLS
thread:1011540
URL: http://www.dr-bob.org/babble/20120221/msgs/1011661.html