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Re: Adding Parnate and prazosin. » SLS

Posted by ed_uk2010 on February 6, 2012, at 6:31:13

In reply to Re: Adding Parnate and prazosin. » ed_uk2010, posted by SLS on February 5, 2012, at 21:53:01

Thanks for the information Scott.

>I see that Fanapt acts like prazosin at the NE alpha-1 receptor. Interesting.

A large number of psych meds are alpha-1 blockers, especially TCAs and many APs (both old and new). This can cause orthostatic hypotension, dizziness and fainting/syncope. Alpha-1 antagonism isn't often thought of as a positive feature of psych meds, but I suppose it could be in some cases.

 

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URL: http://www.dr-bob.org/babble/20120202/msgs/1009441.html